The territory of Vignanello extends to the eastern slopes of the Monti Cimini, surrounded by deep gorges carved by small streams. The area is frequented from the Upper Paleolithic, thanks to the numerous tufa caves scattered around the area in which Homo Sapiens Sapiens could easily find shelter. The settlement was formed during the barbarian invasions, by the population seeking refuge. In 1169 AD Vignanello is conquered by Frederick Barbarossa, who included it in the imperial possessions: later it was disputed by the feudal families of Aldobrandini, Orsini, Di Vico, Farnese (which took the feud in 1534) and finally Ruspoli-Marescotti. The castle was built in the 16th c., designed by Sangallo, above the fortress of the 11th c., that was built by Benedictine monks. In 1611 Ottavia Orsini wanted to add an Italian garden, divided into three different parts.